| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
|
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Product Name: |
Tianeptine sulfate |
| CAS: | 1224690-84-9 |
| MF : | C21H24ClN2NaO4S |
| Grade Standard : | Pharmaceutical grade |
| Specification: | 98%min |
|
Appearance: |
Off- white to white powder |
Tianeptine sulfate is used for treating major depressive episodes (mild, moderate, or severe). It has structural similarities to the tricyclic antidepressants, but it has different pharmacological properties. Tianeptine is a selective serotonin reuptake enhancer (SSRE), opposite to the action of SSRIs. One review points to the cancellative effects of tianeptine and fluoxetine coadministration on serotonin reuptake. Another suggests that long-term administration of tianeptine has no effect on serotonin pathways. Tianeptine enhances the extracellular concentration of dopamine in the nucleus accumbens and modulates the D2 and D3 dopamine receptors. There is also action on the NMDA and AMPA receptors
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
| Product name | Tianeptine sulfate | |
| CAS No. | 1224690-84-9 | |
| Manufacturer Date | 2024.9.20 | |
| Analysis Date | 2024.9.26 | |
| Expire Date | 2026.9.19 | |
| Packaging | 1kg/per sealed bag | |
| Product details | ||
| Appearance | White to off-white crystalline powder | White powder |
| Solubility | Dissolved in N,N-dim, insoluble in water | Complies |
| Impurlties A | 0.1% Max | Not detected |
| Related compounds | Individual impurity substance ≤0.1% | 0.03% |
| Total impurities substance ≤0.4% | 0.02% | |
| Residual solvents (GC) |
EA≤5000ppm | Not detected |
| Methylen chlorid≤600ppm | Not detected | |
| Methan≤3000ppm | Not detected | |
| Aceton≤5000ppm | Not detected | |
| Acetonitril≤410ppm | Not detected | |
| Ethano≤5000ppm | 0.1% | |
| Water | 5.0% max | 3.62% |
| Residue on Ignition | NMT 0.1% | Complies |
| Heavy metals | NMT 10ppm | Complies |
| Assay (by HPLC) | 99.0%~101.0% (on anhydrousbas) | 99.86% |
| Conclusion | This product conforms to enterprise standard | |
Storage: Closed container. Dry & cool. Keep away from moisture &strong light
Shelf life: 24 Months
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