| Powder: | Yes |
|---|---|
| Customized: | Non-Customized |
| Certification: | Kosher |
| Purity: | 99.9% |
| Product Name: | Tianeptine Sodium Salt Powder |
| Other Name: | Tianeptine Sodium Salt |
| Samples: |
|---|
| Customization: |
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|
Product Name: |
Tianeptine Sodium Salt |
| CAS: | 30123-17-2 |
| MF : | C21H24ClN2NaO4S |
| Grade Standard : | Pharmaceutical grade |
| Specification: | 98%min |
|
Appearance: |
Off- white to white powder |
Tianeptine Sodium is a drug used for treating major depressive episodes (mild, moderate, or severe). It has structural similarities to the tricyclic antidepressants, but it has different pharmacological properties. Tianeptine is a selective serotonin reuptake enhancer (SSRE), opposite to the action of SSRIs. One review points to the cancellative effects of tianeptine and fluoxetine coadministration on serotonin reuptake. Another suggests that long-term administration of tianeptine has no effect on serotonin pathways. Tianeptine enhances the extracellular concentration of dopamine in the nucleus accumbens and modulates the D2 and D3 dopamine receptors. There is also action on the NMDA and AMPA receptors
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
| Product Name | Tianeptine Sodium | ||
| Batch Number | Z20180901 | ||
| Production Date | 2018.9. 3 | ||
| Batch Quantity | 24000G | ||
| Analysis Date | 2018.9. 4 | ||
| Expiry Date | 2020.9. 2 | ||
| Certificate Date | 2018.9. 15 | ||
| Item | Test Standard | Testing Result | |
| Assay | Not less than (NLT) 99.5% 99.9% | ||
| TH | Not detected | Undetected | |
| Assay | Method HPLC calculated on the anhydrous basis limit of quotation (LOQ) 0.8ppm | ||
| Appearance | White powder | White powder | |
| Identification | In the recorded chromatograms under the determination of the substance, retention time of the main peak of the solution should be consistent with the retention of time of the main peak of the reference solution | Complies | |
| Melting Point | 65~66ºC | 65.5ºC | |
| Loss on Drying | NMT 1.0% | 0.21% | |
| Residual solvents | Ethanol NMT 400ppm Heptane NMT 400ppm |
1.92ppm 256.0ppm |
|
| Heavy Mental | NMT 20ppm | Complies | |
| Microbial Limite Test | Method: Plate Counting | ||
| Total aerobic bacteria count | NMT 1000cfu/g | Complies | |
| Combined molds and yeast | NMT 100cfu/g | Complies | |
| E. Coli | Not detacted per gram | Complies | |
| Salmanella | Not detacted per 10 gram | Complies | |
| Conclusion: Conform the testing result is qualified | |||
Storage: Closed container. Dry & cool. Keep away from moisture &strong light
Shelf life: 24 Months
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