Best Price Afatinib

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP
• Suitable for: Adult
• State: Solid
• Purity: >99%
• Model NO.: Afatinib
• Product Name: Afatinib
• Botanical Name: Bibw2992
• Brand: Zebrago
• Appearance: White Powder
• Test Method: HPLC
• Molecular Formula: C38h72n2o12
• Use: Endocrine System Agents
• Grade: Phamaceutical Grade
• Function: Phamaceutical Intermediates
• CAS No: 439081-18-2
• Storage: Store in a Cool and Dry Place
• Free Sample: 10 Grams Available
• Apply: for Pah
• Solubility: Soluble in Acetone, Very Slightly Soluble in Hot
• Shipment: by FedEx DHL
• Transport Package: Drum
• Specification: 99% Min
• Trademark: Zebrago
• Origin: China
• HS Code: 2932999099
• Production Capacity: 1000kg/Year

Product Description

Product name	Afatinib
CAS NO.	439081-18-2
Synonyms	Afatinib
Category	Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Purity	99% Afatinib
Appearance	Afatinib characteristic powder
Shelf life	2 years
Usage	Afatinib is an active pharmaceutical ingredient used for antineoplastics
Storage	Afatinib should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.

Afatinib (INN; trade name Gilotrif in the US and Giotrif in Europe, previously Tomtovok and Tovok) is a drug approved in United States, Europe, Taiwan, Mexico, Chile and Japan as well as other countries for the first-line treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim. It acts as an irreversible covalent inhibitor of thereceptor tyrosine kinases epidermal growth factor receptor (EGFR) and erbB-2 (HER2).
 

2. Afatinib is not only active against EGFR mutations targeted by first generation TKIs like erlotinib or gefitinib, but also against mutations such as T790M which are not sensitive to these standard therapies.Because of its additional activity against Her2, it is being investigated for breast cancer as well as other EGFR and Her2 driven cancers.

3. Afatinib is a drug for the first-line treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC).It acts as an irreversible covalent inhibitor of the receptor tyrosine kinases epidermal growth factor receptor (EGFR) and erbB-2 (HER2)

Certificate of Analysis

Batch Number		Z20190412001
Production Date		2019.04.12
Batch Quantity		80 KGS
Item	Test Standard		Testing Result
Appearance	Powder		Complies
Color	White fine Powder		Complies
Particle Size	100% pass 80 mesh		Complies
Oder	Characteristic		Complies
Taste	Characteristic		Complies
Loss on Drying	≤5.0%		2.20%
Residue on Ignition	≤0.1%		0.05%
Residual acetone	≤0.1%		Complies
Residual Ethanol	≤0.5%		Complies
Heave Mentals	≤10ppm		Complies
Na	≤0.1%		<0.1%
Pb	≤3 ppm		Complies
Total Plate	<1000CFU/g		Complies
Yeast & Mold	<100 CFU /g		Complies
E. Coli	Negative		Complies
Salmonella	Negative		Complies
Conclusion: Conform with USP Standard

Storage:Closed container. dry & cool. keep away from moisture &strong light
Shelf life:24 Months  

 

Shipping Options as follows
 

EMS	Around 7-10 working days
DHL	Around 3-5 working days
Fedex	Around 4-6 working days
TNT	Around 6-7 working days
By Air	Around 5-7 working days
By Sea	Around 15-30 working days

     

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